Summary:
- COTI's ecosystem is expanding across healthcare, DeFi, and institutional-grade infrastructure.
- StaTwig processed 10M+ vaccine supply chain transactions in Bangladesh using COTI's Garbled Circuits - with zero sensitive data exposed and under $5 total cost.
- PriveX surpassed $20 billion in trading volume as a privacy-first Perp DEX built on COTI.
- Bancor's Arb Fast Lane bot runs 60,000+ encrypted arbitrage analysis jobs per day using COTI's Garbled Circuits.
- These milestones suggest COTI's privacy infrastructure is moving from theory to large-scale, real-world execution.
Over the past year, COTI's ecosystem has expanded across decentralized finance, real-world asset infrastructure, healthcare systems, and government-aligned implementations etc. As regulatory conversations intensify and institutions explore blockchain integration, networks that can combine transparency with confidentiality are becoming increasingly relevant. COTI's Garbled Circuits-based architecture was built to solve exactly that problem - enabling computation on encrypted data while preserving auditability.
And now, three recent milestones across very different sectors suggest that adoption has started. Firstly, A UN-recognized vaccine supply chain platform running 10 million on-chain transactions in a month. Second, a privacy-first Perpetual DEX surpassing $20 billion in trading volume and third a DeFi pioneer executing 60,000 encrypted arbitrage analyses per day. Let's break down what each milestone means and why together, they tell a much bigger story about where COTI stands today.
StaTwig and Bangladesh: 10 Million Private Health Transactions
In June 2025, COTI announced a partnership with StaTwig, the global supply chain technology company behind VaccineLedger - a UN-recognized Digital Public Good and winner of The Trinity Challenge. The goal was to integrate COTI's blockchain and Garbled Circuits technology into vaccine cold chain monitoring systems used by Bangladesh's public health authorities. Recently they shared the results that are difficult to ignore. COTI's Garbled Circuits are now powering real-time, privacy-preserving vaccine supply chain monitoring in Bangladesh.
During a one-month pilot beginning in December 2025, the system processed over 10 million blockchain transactions. Sensitive health data was never exposed in plaintext. The entire pilot cost approximately 300-400 COTI tokens - under $5 USD at current values. The milestone was summarized clearly:
IoT sensors monitored temperature, humidity, and equipment status across refrigerators and cold rooms at EPI headquarters in Dhaka. Data flowed into VaccineLedger's system, where it was encrypted before ever touching the blockchain. COTI's Garbled Circuits then evaluated business rules such as temperature breach alerts directly on encrypted data. If thresholds were breached, alerts were triggered in real time. Meanwhile, hourly Merkle tree roots were stored on-chain to provide immutable proof that historical data had not been altered.
This pilot validated several critical dimensions of COTI's value proposition like performance at scale, cost efficiency, and privacy that works under real government oversight. Healthcare supply chains demand both transparency and confidentiality. COTI delivered both simultaneously.
PriveX: $20 Billion in Volume on a Privacy-First Perp DEX
The second project milestone brings the conversation back into DeFi but with a privacy-focused edge. PriveX is a privacy-first, intent-based perpetual decentralized exchange built on the COTI Privacy Network. Launched in June 2025, it integrates COTI's Garbled Circuits technology to enable confidential, high-performance trading across more than 550 crypto assets(at the time of writing) and 12 traditional financial assets.
Unlike many decentralized exchanges that expose trade intentions before execution, PriveX protects trader strategy inputs. Execution remains decentralized, but critical thresholds and intent parameters are not visible to competitors. Recently, PriveX crossed a major milestones:
Twenty billion dollars in volume is a significant growth and achievement. It reflects sustained usage by traders who rely on privacy to protect their strategies. For traders operating at scale, visibility can be expensive. If competitors can observe thresholds or execution logic before confirmation, strategies are copied. PriveX leverages COTI's privacy stack to prevent that exposure while maintaining decentralized settlement. Centralized-style liquidity via Symmio is combined with blockchain-based control and privacy enforcement. Traders are choosing to transact through infrastructure that protects their information.
Bancor’s Arb Fast Lane: 60,000 Encrypted Arbitrage Jobs Per Day
The third project milestone comes from one of DeFi's earliest innovators. Bancor has been building liquidity infrastructure since 2016, long before automated market makers became mainstream. Bonding curves, pool tokens, and many foundational AMM mechanics trace back to Bancor's early work. Rather than competing with clones, Bancor evolved and its Carbon DeFi platform introduced programmable, strategy-based liquidity models. And now, through integration with COTI's Garbled Circuits, it has taken arbitrage execution into a new phase.
The Arb Fast Lane is Bancor's on-chain arbitrage trading bot. It continuously monitors price discrepancies across decentralized exchanges. When an opportunity is found, it computes a trade route and executes it but only if profitability thresholds are met. The challenge is that arbitrage thresholds, if visible, can be copied instantly by competing bots. COTI's solution is selective encryption. Sensitive execution inputs such as profitability thresholds are encrypted before broadcast. Smart contracts still enforce the conditions but the thresholds themselves are never revealed to competitors. COTI recently highlighted the scale and said:

Tiago, part of the Bancor and Arb Fast Lane research team, explained the advantage clearly:
This is where privacy moves from theory into competitive advantage. The move changes the dynamic from observation-based extraction to execution-based competition. Also It restores fairness to arbitrage discovery and it runs continuously - 60,000 encrypted analyses per day.
Why These Three Milestones Together Matter
Individually, each of these developments is impressive. But together, they demonstrate something broader: COTI's privacy infrastructure is functioning across three entirely different domains. They represent government use, market-driven adoption, and protocol-level infrastructure. In Bangladesh, a government public health program processed over 10 million vaccine cold-chain transactions in a month. Sensitive health data stayed encrypted the entire time. The system worked, and officials validated it.
In DeFi, PriveX crossed $20 billion in trading volume. That level of activity doesn’t happen without consistent user trust. Traders are choosing to execute strategies on infrastructure that protects their inputs instead of exposing them. At the same time, Bancor’s Arb Fast Lane bot is running more than 60,000 encrypted analysis jobs per day. That’s ongoing, high-frequency activity operating in live markets. The common layer across all three is COTI's implementation of Garbled Circuits. COTI's positioning as a scalable private blockchain for real-world use cases appears increasingly substantiated by activity rather than projections.
The Bigger Picture
Across healthcare, DeFi, and liquidity infrastructure, the same demand appears repeatedly: sensitive data must be processed without exposure. Governments cannot expose patient data. Traders cannot reveal strategy parameters. Arbitrage systems cannot disclose profitability thresholds. Public blockchains traditionally struggle with this balance. Privacy requires additional layers.
COTI's approach embedding Garbled Circuits directly into its Layer 2 architecture - shifts privacy from add-on to built-in. Developers don’t need to choose between transparency and confidentiality. They can process encrypted data on-chain and still get verifiable results. The data stays private and the outcome is enforced. When government programs, active traders, and long-standing DeFi protocols all rely on the same privacy layer, it signals something important. COTI’s infrastructure isn’t waiting for adoption. It’s being used.
Final Thoughts
COTI's ecosystem is rapidly growing and each milestone speaks for itself. Together, they suggest something like privacy-first infrastructure is moving from concept to deployment. If blockchain is going to support real-world systems, it has to handle sensitive data without turning everything into public information. That shift is already happening and these milestones suggest that COTI is already operating inside it.